Sex-dependent association between selenium status and cognitive performance in older adults

B R. Cardoso; DJ Hare; H Macpherson

Journal article

Sex-dependent association between selenium status and cognitive performance in older adults

B R. Cardoso, DJ Hare, H Macpherson

European Journal of Nutrition | SPRINGER HEIDELBERG | Published : 2021

DOI: 10.1007/s00394-020-02384-0

Abstract

Purpose: Selenium (Se) is an essential nutrient required for maintaining brain health across lifespan, and adequate nutritional Se status has been positively associated with sustained cognitive performance in older adults. However, critical physiological sex differences in Se metabolism have not been specifically assessed in human studies. Therefore, we aimed to investigate sex differences in the association between Se concentration in whole blood and cognitive performance in US older adults. Methods: This cross-sectional study included 2016 participants (984 male and 1032 female) ≥ 60 years from the 2011 to 2014 National Health and Nutrition Survey (NHANES). All participants were assessed f..

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University of Melbourne Researchers

Dominic Hare Author

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Grants

Awarded by Agilent Technologies

Funding Acknowledgements

\DJH acknowledged the support of the National Health and Medical Research Council (NHMRC) through the Career Development Fellowship program (GNT1122981). This research did not receive any specific grant from funding agencies in the public, commercial, or notfor-profit sectors.